InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SLC4A8

Summary

InnateDB Protein

IDBP-588398.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC4A8

Protein Name

solute carrier family 4, sodium bicarbonate cotransporter, member 8

Synonyms

NBC3; NDCBE;

Species

Homo sapiens

Ensembl Protein

ENSP00000442561

InnateDB Gene

IDBG-33464 (SLC4A8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0005452	inorganic anion exchanger activity
GO:0008509	anion transmembrane transporter activity

Biological Process

GO:0006810	transport
GO:0006811	ion transport
GO:0006814	sodium ion transport
GO:0006820	anion transport
GO:0015701	bicarbonate transport
GO:0055085	transmembrane transport

Cellular Component

GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR003020 Bicarbonate transporter, eukaryotic
IPR003024 Sodium bicarbonate cotransporter
IPR011531 Bicarbonate transporter, C-terminal
IPR013769 Band 3 cytoplasmic domain
IPR016152 Phosphotransferase/anion transporter

PFAM

PF00955
PF07565

PRINTS

PR01231
PR01232

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q2Y0W8