InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FKBP5

Summary

InnateDB Protein

IDBP-588581.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FKBP5

Protein Name

FK506 binding protein 5

Synonyms

AIG6; FKBP51; FKBP54; P54; PPIase; Ptg-10;

Species

Homo sapiens

Ensembl Protein

ENSP00000442340

InnateDB Gene

IDBG-84259 (FKBP5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 124 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	124 [view]
Protein-Protein	122 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003755	peptidyl-prolyl cis-trans isomerase activity
GO:0005528	FK506 binding
GO:0031072	heat shock protein binding

Biological Process

GO:0000413	protein peptidyl-prolyl isomerization
GO:0006457	protein folding
GO:0061077	chaperone-mediated protein folding

Cellular Component

GO:0005634	nucleus
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR001179 Peptidyl-prolyl cis-trans isomerase, FKBP-type, domain

PFAM

PF00254

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q13451

PhosphoSite

PhosphoSite-Q13451

TrEMBL

UniProt Splice Variant

Entrez Gene

2289

UniGene

Hs.407190

RefSeq

NP_001139249

HUGO

HGNC:3721

OMIM

602623

CCDS

CCDS54996

HPRD

04019

IMGT

EMBL

AB209893 AF194172 AK312422 AL033519 AL157823 AL590400 BC042605 CH471081 U42031 U71321

GenPept

AAA86245 AAC51189 AAH42605 AAL54872 BAD93130 BAG35332 CAI20256 EAX03842