Homo sapiens Protein: PGR
Summary
InnateDB Protein IDBP-588683.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PGR
Protein Name progesterone receptor
Synonyms NR3C3; PR;
Species Homo sapiens
Ensembl Protein ENSP00000432352
InnateDB Gene IDBG-68800 (PGR)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 97 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 97 [view]
Protein-Protein 91 [view]
Protein-DNA 6 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003707 steroid hormone receptor activity
GO:0005496 steroid binding
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0043401 steroid hormone mediated signaling pathway
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000128 Progesterone receptor
IPR000536 Nuclear hormone receptor, ligand-binding, core
IPR001628 Zinc finger, nuclear hormone receptor-type
IPR001723 Steroid hormone receptor
IPR008946 Nuclear hormone receptor, ligand-binding
PFAM PF02161
PF00104
PF00105
PRINTS PR00544
PR00047
PR00398
PIRSF
SMART SM00430
SM00399
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q8NG42
UniProt Splice Variant
Entrez Gene 5241
UniGene Hs.742403
RefSeq
HUGO HGNC:8910
OMIM 607311
CCDS
HPRD 07077
IMGT
EMBL AB085845 AP001533 AY382152 CH471065
GenPept AAQ96834 BAC11013 EAW66997