Version 5.4
Homo sapiens Protein: HMBS
Summary
InnateDB Protein IDBP-588996.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HMBS
Protein Name hydroxymethylbilane synthase
Synonyms PBG-D; PBGD; PORC; UPS;
Species Homo sapiens
Ensembl Protein ENSP00000442079
InnateDB Gene IDBG-547212 (HMBS)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004418 hydroxymethylbilane synthase activity
Biological Process
GO:0033014 tetrapyrrole biosynthetic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000860 Tetrapyrrole biosynthesis, hydroxymethylbilane synthase
IPR022417 Porphobilinogen deaminase, N-terminal
PFAM PF01379
PRINTS PR00151
PIRSF PIRSF001438
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F5GY90
UniProt Splice Variant
Entrez Gene 3145
UniGene
RefSeq
HUGO HGNC:4982
OMIM 609806
CCDS
HPRD 01440
IMGT
EMBL AP003391 AP003392
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca