InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SPDEF

Summary

InnateDB Protein

IDBP-589846.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SPDEF

Protein Name

SAM pointed domain containing ets transcription factor

Synonyms

bA375E1.3; PDEF;

Species

Homo sapiens

Ensembl Protein

ENSP00000442715

InnateDB Gene

IDBG-83610 (SPDEF)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	5 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0007275	multicellular organismal development
GO:0030154	cell differentiation
GO:0043065	positive regulation of apoptotic process