InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PIGG

Summary

InnateDB Protein

IDBP-5902.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PIGG

Protein Name

phosphatidylinositol glycan anchor biosynthesis, class G

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000311750

InnateDB Gene

IDBG-5900 (PIGG)

Protein Structure

UniProt Annotation

Function

Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose. {ECO:0000269PubMed:15632136}.

Subcellular Localization

Endoplasmic reticulum membrane {ECO:0000269PubMed:15632136}; Multi-pass membrane protein {ECO:0000269PubMed:15632136}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0016780	phosphotransferase activity, for other substituted phosphate groups
GO:0051267	CP2 mannose-ethanolamine phosphotransferase activity

Biological Process

GO:0006501	C-terminal protein lipidation
GO:0006506	GPI anchor biosynthetic process
GO:0008152	metabolic process
GO:0016254	preassembly of GPI anchor in ER membrane
GO:0043687	post-translational protein modification
GO:0044267	cellular protein metabolic process