Version 5.4
Homo sapiens Protein: MS4A7
Summary
InnateDB Protein IDBP-590448.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MS4A7
Protein Name membrane-spanning 4-domains, subfamily A, member 7
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000434637
InnateDB Gene IDBG-49027 (MS4A7)
Protein Structure
UniProt Annotation
Function May be involved in signal transduction as a component of a multimeric receptor complex.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Ubiquitous expression in normal tissues. Expression is more elevated in adult liver, lung, spleen, and heart than in their fetal counterparts, and is higher in normal tissues than in the cancerous tissue or cell lines. Low levels of expression were detected in the promonocytic stage, whereas high levels of expression were detected in mature monocytes.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR007237 CD20-like
PFAM PF04103
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9GZW8
PhosphoSite PhosphoSite-Q9GZW8
TrEMBL E9PL98
UniProt Splice Variant
Entrez Gene 58475
UniGene
RefSeq
HUGO HGNC:13378
OMIM 606502
CCDS CCDS7986
HPRD 07579
IMGT
EMBL AB026043 AF201951 AF237916 AF309653 AF350501 AK075106 AK297027 AP003127 BC020673 CH471076 CR457187
GenPept AAF17243 AAG30930 AAH20673 AAK37599 AAL56221 BAB18755 BAC11405 BAG59556 CAG33468 EAW73878 EAW73879 EAW73882

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca