InnateDB Protein
|
IDBP-590771.3
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
GDPD5
|
Protein Name
|
glycerophosphodiester phosphodiesterase domain containing 5
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000433214
|
InnateDB Gene
|
IDBG-64817 (GDPD5)
|
Protein Structure
|
|
Function |
Promotes neurite formation. Cooperates with PRDX1 to drive postmitotic motor neuron differentiation. The glycerophosphodiester phosphodiesterase activity may be required for its role in neuronal differentiation. May contribute to the osmotic regulation of cellular glycerophosphocholine.
|
Subcellular Localization |
Endomembrane system {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Cell projection, growth cone {ECO:0000250}. Note=In a punctate perinuclear pattern. {ECO:0000250}.
|
Disease Associations |
|
Tissue Specificity |
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
Molecular Function |
Accession |
GO Term |
GO:0008081
|
phosphoric diester hydrolase activity
|
GO:0008889
|
glycerophosphodiester phosphodiesterase activity
|
|
Biological Process |
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR017946
PLC-like phosphodiesterase, TIM beta/alpha-barrel domain
|
PFAM |
|
PRINTS |
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q8WTR4
|
PhosphoSite |
PhosphoSite-Q8WTR4
|
TrEMBL |
E9PJU5
|
UniProt Splice Variant |
|
Entrez Gene |
81544
|
UniGene |
Hs.671860
|
RefSeq |
XP_006718757
|
HUGO |
HGNC:28804
|
OMIM |
609632
|
CCDS |
CCDS8238
|
HPRD |
15159
|
IMGT |
|
EMBL |
AF318351
AF318377
AF451987
AK074848
AK098808
AP002815
AY358477
BC018771
BC033391
|
GenPept |
AAH18771
AAH33391
AAL55858
AAL55884
AAP97686
AAQ88841
BAC05418
BAC11242
|
|
|