Version 5.4
Homo sapiens Protein: PROX2
Summary
InnateDB Protein IDBP-591002.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PROX2
Protein Name prospero homeobox 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000451463
InnateDB Gene IDBG-12423 (PROX2)
Protein Structure
UniProt Annotation
Function Transcription regulator. Does not seem to be essential for embryonic development and postnatal survival (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007275 multicellular organismal development
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR009057 Homeodomain-like
IPR023082 Homeo-prospero domain
PFAM PF05044
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3B8N5
PhosphoSite PhosphoSite-Q3B8N5
TrEMBL
UniProt Splice Variant
Entrez Gene 283571
UniGene Hs.675293
RefSeq NP_001073877
HUGO HGNC:26715
OMIM 615094
CCDS CCDS45136
HPRD
IMGT
EMBL AC006530 AK094068 BC105720 BC105927
GenPept AAI05721 AAI05928 BAC04278

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca