Version 5.4
Homo sapiens Protein: PLEKHA5
Summary
InnateDB Protein IDBP-591256.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLEKHA5
Protein Name pleckstrin homology domain containing, family A member 5
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000439673
InnateDB Gene IDBG-22083 (PLEKHA5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm {ECO:0000269PubMed:22037487}.
Disease Associations
Tissue Specificity Highly expressed in heart and kidney. {ECO:0000269PubMed:11001876}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 36 experimentally validated interaction(s) in this database.
Experimentally validated
Total 36 [view]
Protein-Protein 35 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005545 1-phosphatidylinositol binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001202 WW domain
IPR001849 Pleckstrin homology domain
PFAM PF00397
PF00169
PRINTS
PIRSF
SMART SM00456
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9HAU0
PhosphoSite PhosphoSite-Q9HAU0
TrEMBL F5H1X3
UniProt Splice Variant
Entrez Gene 54477
UniGene Hs.732805
RefSeq NP_001137293
HUGO HGNC:30036
OMIM 607770
CCDS CCDS44840
HPRD 09684
IMGT
EMBL AB051473 AB642244 AC024902 AC087314 AC091805 AC092828 AF302150 AK001529 AK023127 AK294739 AL834259 BC000969 BC013133 BC044245 BC070174 BC127092 CH471094
GenPept AAG22817 AAH00969 AAH13133 AAH44245 AAH70174 AAI27093 BAA91742 BAB14419 BAB21777 BAG57882 BAL45489 CAD38934 EAW96392 EAW96393 EAW96395

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca