Version 5.4
Homo sapiens Protein: RELA
Summary
InnateDB Protein IDBP-592201.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RELA
Protein Name v-rel reticuloendotheliosis viral oncogene homolog A (avian)
Synonyms NFKB3; p65;
Species Homo sapiens
Ensembl Protein ENSP00000435290
InnateDB Gene IDBG-57543 (RELA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 570 experimentally validated interaction(s) in this database.
They are also associated with 108 interaction(s) predicted by orthology.
Experimentally validated
Total 570 [view]
Protein-Protein 407 [view]
Protein-DNA 157 [view]
Protein-RNA 0
DNA-DNA 6 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 108 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR000451 NF-kappa-B/Rel/Dorsal
IPR008967 p53-like transcription factor, DNA-binding
IPR011539 Rel homology domain
IPR014756 Immunoglobulin E-set
PFAM PF00554
PRINTS PR00057
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q96F54
UniProt Splice Variant
Entrez Gene 5970
UniGene Hs.502875
RefSeq
HUGO HGNC:9955
OMIM 164014
CCDS
HPRD 01241
IMGT
EMBL AP001362 BC011603
GenPept AAH11603

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca