InnateDB Protein
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IDBP-592912.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NFRKB
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Protein Name
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nuclear factor related to kappaB binding protein
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Synonyms
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INO80G;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000433572
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InnateDB Gene
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IDBG-76076 (NFRKB)
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Protein Structure
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Function |
Binds to the DNA consensus sequence 5'-GGGGAATCTCC-3'. {ECO:0000269PubMed:18922472}.Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Modulates the deubiquitinase activity of UCHL5 in the INO80 complex. {ECO:0000269PubMed:18922472}.
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Subcellular Localization |
Nucleus {ECO:0000269PubMed:18922472}.
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Disease Associations |
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Tissue Specificity |
Expressed in thymus, brain, testes, spleen and liver. {ECO:0000269PubMed:1777480}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
28
[view]
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Protein-Protein |
28
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q6P4R8
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PhosphoSite |
PhosphoSite-Q6P4R8
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TrEMBL |
E9PM88
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UniProt Splice Variant |
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Entrez Gene |
4798
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UniGene |
Hs.607279
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RefSeq |
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HUGO |
HGNC:7802
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OMIM |
164013
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CCDS |
CCDS44770
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HPRD |
01240
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IMGT |
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EMBL |
AL512730
AP003327
BC063280
CH471065
U08191
X80878
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GenPept |
AAA17871
AAH63280
CAA56846
CAC21663
EAW67755
EAW67757
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