Version 5.4
Homo sapiens Protein: NEU3
Summary
InnateDB Protein IDBP-593097.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NEU3
Protein Name sialidase 3 (membrane sialidase)
Synonyms SIAL3;
Species Homo sapiens
Ensembl Protein ENSP00000432097
InnateDB Gene IDBG-64552 (NEU3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004308 exo-alpha-sialidase activity
GO:0016997 alpha-sialidase activity
GO:0052794 exo-alpha-(2->3)-sialidase activity
GO:0052795 exo-alpha-(2->6)-sialidase activity
GO:0052796 exo-alpha-(2->8)-sialidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006665 sphingolipid metabolic process
GO:0006687 glycosphingolipid metabolic process
GO:0006689 ganglioside catabolic process
GO:0008152 metabolic process
GO:0009313 oligosaccharide catabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
Protein Structure and Domains
PDB ID
InterPro IPR011040 Sialidases
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B4E0V4
UniProt Splice Variant
Entrez Gene 10825
UniGene Hs.606201
RefSeq
HUGO HGNC:7760
OMIM 604617
CCDS CCDS44682
HPRD 05215
IMGT
EMBL AB008185 AK022450 AK290442 AK303540 AP001992 BC136397 BC144059 CH471076 Y18563
GenPept AAI36398 AAI44060 BAA82611 BAF83131 BAG51074 BAG64566 CAB96131 EAW74953 EAW74954

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca