Homo sapiens Protein: UBE2L3
Summary
InnateDB Protein IDBP-594947.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UBE2L3
Protein Name ubiquitin-conjugating enzyme E2L 3
Synonyms E2-F1; L-UBC; UBCH7; UbcM4;
Species Homo sapiens
Ensembl Protein ENSP00000445931
InnateDB Gene IDBG-2059 (UBE2L3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 128 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 128 [view]
Protein-Protein 128 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016881 acid-amino acid ligase activity
GO:0019899 enzyme binding
GO:0031625 ubiquitin protein ligase binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000209 protein polyubiquitination
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006464 cellular protein modification process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0008283 cell proliferation
GO:0016567 protein ubiquitination
GO:0070979 protein K11-linked ubiquitination
GO:0071383 cellular response to steroid hormone stimulus
GO:0071385 cellular response to glucocorticoid stimulus
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000608 Ubiquitin-conjugating enzyme, E2
IPR006575 RWD domain
IPR016135 Ubiquitin-conjugating enzyme/RWD-like
PFAM PF00179
PF05773
PRINTS
PIRSF
SMART SM00591
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P68036
PhosphoSite PhosphoSite-P68036
TrEMBL
UniProt Splice Variant
Entrez Gene 7332
UniGene Hs.613248
RefSeq NP_001243285
HUGO HGNC:12488
OMIM 603721
CCDS CCDS58796
HPRD 04762
IMGT
EMBL AF300336 AJ000519 AK293179 AK299985 AK311761 AP000553 AP000557 AP000558 BC053368 CH471095 CR456606 S81003 X92962
GenPept AAB36017 AAG17922 AAH53368 BAG34704 BAG56722 BAG61806 CAA04156 CAA63538 CAG30492 EAW59459