InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RBM4B

Summary

InnateDB Protein

IDBP-59548.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RBM4B

Protein Name

RNA binding motif protein 4B

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000310471

InnateDB Gene

IDBG-59546 (RBM4B)

Protein Structure

UniProt Annotation

Function

Required for the translational activation of PER1 mRNA in response to circadian clock. Binds directly to the 3'-UTR of the PER1 mRNA (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus. Nucleus, nucleolus.

Disease Associations

Tissue Specificity

Expressed in liver and kidney (at protein level). Ubiquitously expressed. {ECO:0000269PubMed:12628928, ECO:0000269PubMed:18708123}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006397	mRNA processing
GO:0006417	regulation of translation
GO:0007623	circadian rhythm
GO:0008380	RNA splicing
GO:0032922	circadian regulation of gene expression
GO:0043153	entrainment of circadian clock by photoperiod