InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FMNL3

Summary

InnateDB Protein

IDBP-595645.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FMNL3

Protein Name

formin-like 3

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000447479

InnateDB Gene

IDBG-31836 (FMNL3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.

Experimentally validated
Total	9 [view]
Protein-Protein	9 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0005488	binding
GO:0017048	Rho GTPase binding
GO:0032794	GTPase activating protein binding

Biological Process

GO:0007010	cytoskeleton organization
GO:0008360	regulation of cell shape
GO:0016043	cellular component organization
GO:0016477	cell migration
GO:0030036	actin cytoskeleton organization

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

InterPro

IPR010472 Formin, FH3 domain
IPR010473 Formin, GTPase-binding domain
IPR015425 Formin, FH2 domain
IPR016024 Armadillo-type fold

PFAM

PF06367
PF06371
PF02181

PRINTS

PIRSF

SMART

SM00498

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F8W1F5

UniProt Splice Variant

Entrez Gene

91010

UniGene

Hs.708422

RefSeq

XP_005269275

HUGO

HGNC:23698

OMIM

CCDS

HPRD

17007

IMGT

EMBL

AB095934 AC020612 AK128195 BC159100

GenPept

AAI59101 BAC23110 BAC87319