Version 5.4
Homo sapiens Protein: TMEM109
Summary
InnateDB Protein IDBP-595986.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM109
Protein Name transmembrane protein 109
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000443990
InnateDB Gene IDBG-49461 (TMEM109)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Nucleus outer membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Sarcoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0060548 negative regulation of cell death
GO:0071480 cellular response to gamma radiation
Cellular Component
GO:0005640 nuclear outer membrane
GO:0016021 integral component of membrane
GO:0033017 sarcoplasmic reticulum membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BVC6
PhosphoSite PhosphoSite-Q9BVC6
TrEMBL
UniProt Splice Variant
Entrez Gene 79073
UniGene Hs.13662
RefSeq
HUGO HGNC:28771
OMIM
CCDS CCDS7996
HPRD 14687
IMGT
EMBL BC001309
GenPept AAH01309

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca