Version 5.4
Homo sapiens Protein: PNP
Summary
InnateDB Protein IDBP-598839.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PNP
Protein Name purine nucleoside phosphorylase
Synonyms NP; PRO1837; PUNP;
Species Homo sapiens
Ensembl Protein ENSP00000452421
InnateDB Gene IDBG-2272 (PNP)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
Experimentally validated
Total 28 [view]
Protein-Protein 27 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004731 purine-nucleoside phosphorylase activity
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0009116 nucleoside metabolic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000845 Nucleoside phosphorylase domain
IPR011268 Purine nucleoside phosphorylase
PFAM PF01048
PRINTS
PIRSF PIRSF000477
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3V5M2
UniProt Splice Variant
Entrez Gene 4860
UniGene Hs.75514
RefSeq
HUGO HGNC:7892
OMIM 164050
CCDS
HPRD 01247
IMGT
EMBL AL355075
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca