Version 5.4
Homo sapiens Protein: ZCCHC8
Summary
InnateDB Protein IDBP-599017.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZCCHC8
Protein Name zinc finger, CCHC domain containing 8
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000438993
InnateDB Gene IDBG-62552 (ZCCHC8)
Protein Structure
UniProt Annotation
Function May be involved in pre-mRNA splicing.
Subcellular Localization Nucleus, nucleoplasm {ECO:0000269PubMed:21855801}. Note=Excluded from nucleolus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 37 [view]
Protein-Protein 37 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0071013 catalytic step 2 spliceosome
Protein Structure and Domains
PDB ID
InterPro IPR006568 PSP, proline-rich
PFAM PF04046
PRINTS
PIRSF
SMART SM00581
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6NZY4
PhosphoSite PhosphoSite-Q6NZY4
TrEMBL F5H803
UniProt Splice Variant
Entrez Gene 55596
UniGene Hs.699539
RefSeq NP_060082
HUGO HGNC:25265
OMIM
CCDS
HPRD 11698
IMGT
EMBL AC127002 AK027702 AK074638 AL157433 AL157434 BC017704 BC065918
GenPept AAH17704 AAH65918 BAB55308 BAC11105 CAB75657 CAB75658

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca