Version 5.4
Homo sapiens Protein: DCAF5
Summary
InnateDB Protein IDBP-599156.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DCAF5
Protein Name DDB1 and CUL4 associated factor 5
Synonyms BCRG2; BCRP2; D14S1461E; WDR22;
Species Homo sapiens
Ensembl Protein ENSP00000452052
InnateDB Gene IDBG-10256 (DCAF5)
Protein Structure
UniProt Annotation
Function May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. {ECO:0000269PubMed:16949367, ECO:0000269PubMed:16964240}.
Subcellular Localization
Disease Associations
Tissue Specificity Ubiquitous. {ECO:0000269PubMed:9740667}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
GO:0080008 Cul4-RING E3 ubiquitin ligase complex
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
PFAM PF00400
PRINTS
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96JK2
PhosphoSite PhosphoSite-Q96JK2
TrEMBL Q8NCX5
UniProt Splice Variant
Entrez Gene 8816
UniGene Hs.708592
RefSeq
HUGO HGNC:20224
OMIM 603812
CCDS CCDS61480
HPRD 16032
IMGT
EMBL AB058727 AF044774 AL831823 AL831932 AL834533 BC136632 CH471061
GenPept AAC08965 AAI36633 BAB47453 CAD38537 CAD38589 CAD39189 EAW80983

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca