Version 5.4
Homo sapiens Protein: FAM213B
Summary
InnateDB Protein IDBP-599214.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAM213B
Protein Name chromosome 1 open reading frame 93
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000443605
InnateDB Gene IDBG-86442 (FAM213B)
Protein Structure
UniProt Annotation
Function Catalyzes the reduction of prostaglandin-ethanolamide H(2) (prostamide H(2)) to prostamide F(2alpha) with NADPH as proton donor. Also able to reduce prostaglandin H(2) to prostaglandin F(2alpha) (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytosol {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0047017 prostaglandin-F synthase activity
Biological Process
GO:0001516 prostaglandin biosynthetic process
GO:0019369 arachidonic acid metabolic process
GO:0019371 cyclooxygenase pathway
GO:0044281 small molecule metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0043209 myelin sheath
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR012336 Thioredoxin-like fold
PFAM PF13098
PF13192
PF13462
PF13905
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8TBF2
PhosphoSite PhosphoSite-Q8TBF2
TrEMBL
UniProt Splice Variant
Entrez Gene 127281
UniGene Hs.462033
RefSeq NP_001182670
HUGO HGNC:28390
OMIM
CCDS CCDS55564
HPRD 14513
IMGT
EMBL AF425266 AK057027 AK075273 AK291908 AK298926 AK303504 AK316243 AL139246 BC022547 CH471183
GenPept AAH22547 AAP97295 BAC11511 BAF84597 BAG51845 BAG61031 BAG64537 BAH14614 CAX30825 CAX30826 CAX30827 EAW56086 EAW56087 EAW56088

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca