InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MAPK3

Summary

InnateDB Protein

IDBP-601246.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MAPK3

Protein Name

mitogen-activated protein kinase 3

Synonyms

ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; p44-ERK1; p44-MAPK; P44ERK1; P44MAPK; PRKM3;

Species

Homo sapiens

Ensembl Protein

ENSP00000432292

InnateDB Gene

IDBG-25745 (MAPK3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 238 experimentally validated interaction(s) in this database.

Experimentally validated
Total	238 [view]
Protein-Protein	236 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004707	MAP kinase activity
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0000165	MAPK cascade
GO:0006468	protein phosphorylation

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR008349 Mitogen-activated protein (MAP) kinase, ERK1/2
IPR011009 Protein kinase-like domain

PFAM

PF00069

PRINTS

PR01770

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

E9PRH7

UniProt Splice Variant

Entrez Gene

5595

UniGene

Hs.861

RefSeq

HUGO

HGNC:6877

OMIM

601795

CCDS

HPRD

03479

IMGT

EMBL

AC012645

GenPept