Version 5.4
Homo sapiens Protein: B2M
Summary
InnateDB Protein IDBP-601739.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol B2M
Protein Name beta-2-microglobulin
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000453023
InnateDB Gene IDBG-9902 (B2M)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 188 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 188 [view]
Protein-Protein 175 [view]
Protein-DNA 9 [view]
Protein-RNA 4 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0042612 MHC class I protein complex
Protein Structure and Domains
PDB ID
InterPro IPR003597 Immunoglobulin C1-set
IPR007110 Immunoglobulin-like domain
PFAM PF07654
PRINTS
PIRSF
SMART SM00407
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9UM88
UniProt Splice Variant
Entrez Gene 567
UniGene Hs.623704
RefSeq XP_005254606
HUGO HGNC:914
OMIM 109700
CCDS
HPRD 00189
IMGT
EMBL AC025270 AC122108 S82300
GenPept AAD14388

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca