Version 5.4
Homo sapiens Protein: IRX5
Summary
InnateDB Protein IDBP-603188.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IRX5
Protein Name iroquois homeobox 5
Synonyms HMMS; IRX-2a; IRXB2;
Species Homo sapiens
Ensembl Protein ENSP00000453725
InnateDB Gene IDBG-31208 (IRX5)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005499 vitamin D binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007601 visual perception
GO:0008406 gonad development
GO:0048701 embryonic cranial skeleton morphogenesis
GO:0050896 response to stimulus
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR003893 Iroquois-class homeodomain protein
IPR009057 Homeodomain-like
PFAM PF00046
PRINTS
PIRSF
SMART SM00389
SM00548
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P78411
PhosphoSite PhosphoSite-P78411
TrEMBL
UniProt Splice Variant
Entrez Gene 10265
UniGene Hs.435730
RefSeq
HUGO HGNC:14361
OMIM 606195
CCDS
HPRD 08395
IMGT
EMBL AC106738 AY335944 AY335945 U90304 U90309
GenPept AAB50002 AAB50007 AAQ16550 AAQ16551

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca