InnateDB Protein
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IDBP-603677.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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ORMDL2
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Protein Name
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ORM1-like 2 (S. cerevisiae)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000448788
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InnateDB Gene
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IDBG-39159 (ORMDL2)
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Protein Structure
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Function |
Negative regulator of sphingolipid synthesis. {ECO:0000269PubMed:20182505}.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000269PubMed:12093374}; Multi-pass membrane protein {ECO:0000269PubMed:12093374}.
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Disease Associations |
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Tissue Specificity |
Widely expressed. Expressed in adult and fetal heart, brain, lung, liver, skeletal muscle and kidney. Expressed in adult pancreas and placenta and in fetal spleen abd thymus. {ECO:0000269PubMed:12093374}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
2
[view]
|
Protein-Protein |
1
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR007203
ORMDL
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PFAM |
PF04061
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PRINTS |
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PIRSF |
PIRSF018147
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q53FV1
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PhosphoSite |
PhosphoSite-Q53FV1
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TrEMBL |
F8VXD5
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UniProt Splice Variant |
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Entrez Gene |
29095
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UniGene |
Hs.734057
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RefSeq |
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HUGO |
HGNC:16037
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OMIM |
610074
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CCDS |
CCDS8893
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HPRD |
17802
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IMGT |
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EMBL |
AB064961
AC023055
AF161509
AF173375
AF395705
AF395706
AF395707
AK223180
AK314046
BC012543
CH471054
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GenPept |
AAF29124
AAH12543
AAM43504
AAM43505
AAM43506
AAQ13618
BAC11712
BAD96900
BAG36755
EAW96840
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