Homo sapiens Protein: STX3
Summary
InnateDB Protein IDBP-603939.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STX3
Protein Name syntaxin 3
Synonyms STX3A;
Species Homo sapiens
Ensembl Protein ENSP00000433248
InnateDB Gene IDBG-48547 (STX3)
Protein Structure
UniProt Annotation
Function Potentially involved in docking of synaptic vesicles at presynaptic active zones.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005484 SNAP receptor activity
GO:0005515 protein binding
GO:0050544 arachidonic acid binding
Biological Process
GO:0006836 neurotransmitter transport
GO:0006886 intracellular protein transport
GO:0016192 vesicle-mediated transport
GO:0031175 neuron projection development
Cellular Component
GO:0005773 vacuole
GO:0005911 cell-cell junction
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0030426 growth cone
GO:0031201 SNARE complex
GO:0042581 specific granule
GO:0042582 azurophil granule
GO:0043005 neuron projection
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000727 Target SNARE coiled-coil domain
IPR006011 Syntaxin, N-terminal domain
IPR010989 t-SNARE
PFAM PF05739
PF00804
PRINTS
PIRSF
SMART SM00397
SM00503
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q13277
PhosphoSite PhosphoSite-Q13277
TrEMBL
UniProt Splice Variant
Entrez Gene 6809
UniGene Hs.593594
RefSeq NP_001171511
HUGO HGNC:11438
OMIM 600876
CCDS CCDS53637
HPRD 15985
IMGT
EMBL AJ002076 AJ002077 AK297419 AP000640 BC007405 BC007429 CH471076 U32315 X90581
GenPept AAA75303 AAH07405 AAH07429 BAG59852 CAA05175 CAA05176 CAA62209 EAW73854