Version 5.4
Homo sapiens Protein: POP5
Summary
InnateDB Protein IDBP-60810.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POP5
Protein Name processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000341791
InnateDB Gene IDBG-60808 (POP5)
Protein Structure
UniProt Annotation
Function Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP. {ECO:0000269PubMed:11413139}.
Subcellular Localization Nucleus, nucleolus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 6 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004526 ribonuclease P activity
GO:0004540 ribonuclease activity
GO:0005515 protein binding
Biological Process
GO:0008033 tRNA processing
GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002759 Ribonuclease P/MRP protein subunit
PFAM PF01900
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q969H6
PhosphoSite PhosphoSite-Q969H6
TrEMBL
UniProt Splice Variant
Entrez Gene 51367
UniGene
RefSeq NP_937845
HUGO HGNC:17689
OMIM 609992
CCDS CCDS9203
HPRD 15158
IMGT
EMBL AC063943 AF070660 AF117232 AJ306296 AK223206 AK303144 BC012505 CH471054
GenPept AAD20966 AAF17213 AAH12505 BAD96926 BAG64248 CAC59822 EAW98206

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca