InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PVALB

Summary

InnateDB Protein

IDBP-6092.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PVALB

Protein Name

parvalbumin

Synonyms

D22S749;

Species

Homo sapiens

Ensembl Protein

ENSP00000216200

InnateDB Gene

IDBG-6090 (PVALB)

Protein Structure

UniProt Annotation

Function

In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0042803	protein homodimerization activity
GO:0046982	protein heterodimerization activity

Biological Process

GO:0051480

cytosolic calcium ion homeostasis

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0030424	axon
GO:0043025	neuronal cell body
GO:0043234	protein complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR002048 EF-hand domain

PFAM

PF00036
PF13202
PF13405

PRINTS

PIRSF

SMART

SM00054

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P20472

PhosphoSite

PhosphoSite-P20472

TrEMBL

B8ZZ19

UniProt Splice Variant

Entrez Gene

5816

UniGene

Hs.708513

RefSeq

NP_002845

HUGO

HGNC:9704

OMIM

168890

CCDS

CCDS13933

HPRD

01353

IMGT

EMBL

AK311832 BC069300 BC096112 BC096113 BC096114 BC096115 CH471095 CR456552 X52695 X52696 X52697 X52698 X63070 X63578 Z82184 Z82185

GenPept

AAH69300 AAH96112 AAH96113 AAH96114 AAH96115 BAG34774 CAA36924 CAA44792 CAA45134 CAG30438 CAI23584 CAI23585 EAW60118 EAW60120 EAW60121