Version 5.4
Homo sapiens Protein: TMEM14C
Summary
InnateDB Protein IDBP-61146.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM14C
Protein Name transmembrane protein 14C
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000229563
InnateDB Gene IDBG-61144 (TMEM14C)
Protein Structure
UniProt Annotation
Function Required for normal heme biosynthesis. {ECO:0000250}.
Subcellular Localization Mitochondrion membrane {ECO:0000250}; Multi- pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
Experimentally validated
Total 7 [view]
Protein-Protein 7 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006783 heme biosynthetic process
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031966 mitochondrial membrane
Protein Structure and Domains
PDB ID
InterPro IPR005349 Uncharacterised protein family UPF0136, Transmembrane
PFAM PF03647
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9P0S9
PhosphoSite PhosphoSite-
TrEMBL A0A024R001
UniProt Splice Variant
Entrez Gene 51522
UniGene Hs.627030
RefSeq NP_057546
HUGO HGNC:20952
OMIM 615318
CCDS CCDS4514
HPRD 15524
IMGT
EMBL AF151028 AL358777 BC002496 BC010086 CH471087
GenPept AAF36114 AAH02496 AAH10086 CAI14003 EAW55271 EAW55272 EAW55273

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca