InnateDB Protein
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IDBP-61805.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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GINS1
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Protein Name
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GINS complex subunit 1 (Psf1 homolog)
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Synonyms
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PSF1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000262460
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InnateDB Gene
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IDBG-61803 (GINS1)
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Protein Structure
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Function |
The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single- stranded DNA. GINS1 is essential for function. {ECO:0000269PubMed:17417653}.
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Subcellular Localization |
Nucleus {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
6
[view]
|
Protein-Protein |
5
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
1
[view]
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q14691
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PhosphoSite |
PhosphoSite-Q14691
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
9837
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UniGene |
Hs.658464
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RefSeq |
NP_066545
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HUGO |
HGNC:28980
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OMIM |
610608
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CCDS |
CCDS33451
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HPRD |
11067
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IMGT |
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EMBL |
AL031672
AL353812
BC012542
D80008
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GenPept |
AAH12542
BAA11503
CAI13764
CAI43019
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