InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Nrsn1

Summary

InnateDB Protein

IDBP-619828.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nrsn1

Protein Name

neurensin 1

Synonyms

Neurensin-1; Neuro-p24; Vmp;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000128979

InnateDB Gene

IDBG-139794 (Nrsn1)

Protein Structure

UniProt Annotation

Function

May play an important role in neural organelle transport, and in transduction of nerve signals or in nerve growth. May play a role in neurite extension. {ECO:0000269PubMed:12445626, ECO:0000269PubMed:16527258, ECO:0000269PubMed:16696124, ECO:0000269PubMed:9191101}.

Subcellular Localization

Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Localizes mainly to neurites. {ECO:0000269PubMed:16527258}.

Disease Associations

Tissue Specificity

Expressed predominantly in brain. Also weakly expressed in lung and spleen. In brain, expressed strongly in nerve fibers of the cerebral cortex, anterior cerebral nuclei, hypothalamus, amygdaloid complex, brain stem of the metaencephalon and medulla oblongata, and moderately expressed in soma of neurons of the dentate gyrus of the hippocampus and Purkinje cells of the cerebellum. {ECO:0000269PubMed:9191101}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0007399	nervous system development
GO:0008150	biological_process

Cellular Component

GO:0016021	integral component of membrane
GO:0016023	cytoplasmic membrane-bounded vesicle
GO:0030133	transport vesicle
GO:0030426	growth cone
GO:0043005	neuron projection
GO:0043025	neuronal cell body