Version 5.4
Mus musculus Protein: Slc6a17
Summary
InnateDB Protein IDBP-619895.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc6a17
Protein Name solute carrier family 6 (neurotransmitter transporter), member 17
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000131888
InnateDB Gene IDBG-185267 (Slc6a17)
Protein Structure
UniProt Annotation
Function Functions as a sodium-dependent vesicular transporter selective for proline, glycine, leucine and alanine. In contrast to other members of this neurotransmitter transporter family, does not appear to be chloride-dependent (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005328 neurotransmitter:sodium symporter activity
Biological Process
GO:0006836 neurotransmitter transport
GO:0015804 neutral amino acid transport
GO:0015816 glycine transport
GO:0015820 leucine transport
GO:0015824 proline transport
GO:0032328 alanine transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005575 cellular_component
GO:0005887 integral component of plasma membrane
GO:0008021 synaptic vesicle
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0030672 synaptic vesicle membrane
Protein Structure and Domains
PDB ID MGI:2442535
InterPro IPR000175 Sodium:neurotransmitter symporter
IPR002438 Sodium:neurotransmitter symporter, orphan
PFAM PF00209
PRINTS PR00176
PR01206
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8BJI1
PhosphoSite PhosphoSite-Q8BJI1
TrEMBL
UniProt Splice Variant
Entrez Gene 229706
UniGene Mm.212867
RefSeq
MGI ID
MGI Symbol Slc6a17
OMIM
CCDS
HPRD
IMGT
EMBL AK032262 AK083807 AY155578 BC141148 BC171962
GenPept AAI41149 AAI71962 AAN75010 BAC27785 BAC39024

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca