Mus musculus Protein: Pdc
Summary
InnateDB Protein IDBP-620188.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pdc
Protein Name phosducin
Synonyms Rpr-1; Rpr1;
Species Mus musculus
Ensembl Protein ENSMUSP00000131631
InnateDB Gene IDBG-197384 (Pdc)
Protein Structure
UniProt Annotation
Function Inhibits the transcriptional activation activity of the cone-rod homeobox CRX (By similarity). May participate in the regulation of visual phototransduction or in the integration of photoreceptor metabolism. {ECO:0000250}.
Subcellular Localization Cytoplasm, cytosol. Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment. Nucleus {ECO:0000250}. Note=Outer and inner segments of the rod cells.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007601 visual perception
GO:0050896 response to stimulus
Cellular Component
GO:0001750 photoreceptor outer segment
GO:0001917 photoreceptor inner segment
GO:0005634 nucleus
GO:0005829 cytosol
GO:0015629 actin cytoskeleton
Protein Structure and Domains
PDB ID MGI:98090
InterPro IPR001200 Phosducin
IPR012336 Thioredoxin-like fold
IPR024253 Phosducin, thioredoxin-like domain
PFAM PF13098
PF13192
PF13462
PF13905
PF02114
PRINTS PR00677
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9QW08
PhosphoSite PhosphoSite-Q9QW08
TrEMBL
UniProt Splice Variant
Entrez Gene 20028
UniGene
RefSeq NP_001153202
MGI ID
MGI Symbol Pdc
OMIM
CCDS CCDS15354
HPRD
IMGT
EMBL BC012507 BC021920 L08075
GenPept AAH12507 AAH21920 AAK13559