InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ap1g2

Summary

InnateDB Protein

IDBP-620224.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ap1g2

Protein Name

adaptor protein complex AP-1, gamma 2 subunit

Synonyms

Adtg2; G2ad;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000128427

InnateDB Gene

IDBG-163064 (Ap1g2)

Protein Structure

UniProt Annotation

Function

May function in protein sorting in late endosomes or multivesucular bodies (MVBs).

Subcellular Localization

Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cytoplasmic vesicle membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Endosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Widely expressed.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0008565	protein transporter activity

Biological Process

GO:0006886	intracellular protein transport
GO:0015031	protein transport
GO:0016192	vesicle-mediated transport

Cellular Component

GO:0000139	Golgi membrane
GO:0005794	Golgi apparatus
GO:0005798	Golgi-associated vesicle
GO:0005802	trans-Golgi network
GO:0010008	endosome membrane
GO:0016020	membrane
GO:0030117	membrane coat
GO:0030131	clathrin adaptor complex
GO:0030133	transport vesicle
GO:0030659	cytoplasmic vesicle membrane

Protein Structure and Domains

PDB ID

MGI:1328307

InterPro

IPR002553 Clathrin/coatomer adaptor, adaptin-like, N-terminal
IPR008152 Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain
IPR008153 Clathrin adaptor, gamma-adaptin, appendage
IPR013041 Coatomer/clathrin adaptor appendage, Ig-like subdomain
IPR016024 Armadillo-type fold
IPR017107 Adaptor protein complex AP-1, gamma subunit

PFAM

PF01602
PF02883

PRINTS

PIRSF

PIRSF037094

SMART

SM00809

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt