InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Naalad2

Summary

InnateDB Protein

IDBP-620371.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Naalad2

Protein Name

N-acetylated alpha-linked acidic dipeptidase 2

Synonyms

2700022G20Rik; D9Ertd285e; Folh1b; GCP3; GCPIII; NAADALASE2; NAALADASE2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000128674

InnateDB Gene

IDBG-136145 (Naalad2)

Protein Structure

UniProt Annotation

Function

Has N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Also exhibits a dipeptidyl-peptidase IV type activity. Inactivate the peptide neurotransmitter N- acetylaspartylglutamate. {ECO:0000269PubMed:15086519}.

Subcellular Localization

Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.

Disease Associations

Tissue Specificity

Expressed ovary, testes and lung, but not brain. {ECO:0000269PubMed:15086519}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004180	carboxypeptidase activity
GO:0008233	peptidase activity
GO:0008237	metallopeptidase activity
GO:0016805	dipeptidase activity
GO:0046872	metal ion binding
GO:0050129	N-formylglutamate deformylase activity