Version 5.4
Mus musculus Protein: Smarca4
Summary
InnateDB Protein IDBP-620582.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Smarca4
Protein Name SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Synonyms b2b508.1Clo; b2b692Clo; Brg1; HP1-BP72; SNF2beta; SW1/SNF;
Species Mus musculus
Ensembl Protein ENSMUSP00000133535
InnateDB Gene IDBG-141000 (Smarca4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 144 experimentally validated interaction(s) in this database.
They are also associated with 200 interaction(s) predicted by orthology.
Experimentally validated
Total 144 [view]
Protein-Protein 122 [view]
Protein-DNA 17 [view]
Protein-RNA 0
DNA-DNA 5 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 200 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016817 hydrolase activity, acting on acid anhydrides
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID MGI:88192
InterPro IPR000330 SNF2-related
IPR001650 Helicase, C-terminal
IPR006576 BRK domain
IPR013999 HAS subgroup
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR014012 Helicase/SANT-associated, DNA binding
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00176
PF00271
PF07533
PF07529
PRINTS
PIRSF
SMART SM00490
SM00592
SM00573
SM00487
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q3URH5
UniProt Splice Variant
Entrez Gene 20586
UniGene Mm.286593
RefSeq
MGI ID
MGI Symbol Smarca4
OMIM
CCDS
HPRD
IMGT
EMBL AK141517
GenPept BAE24713

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca