Version 5.4
Mus musculus Protein: Myl6
Summary
InnateDB Protein IDBP-620655.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Myl6
Protein Name myosin, light polypeptide 6, alkali, smooth muscle and non-muscle
Synonyms ESMLC; LC17; LC17-GI; LC17-NM; LC17A; LC17B; MLC-3; MLC1SM; MLC3nm; MLC3SM; Myln;
Species Mus musculus
Ensembl Protein ENSMUSP00000128803
InnateDB Gene IDBG-605265 (Myl6)
Protein Structure
UniProt Annotation
Function Regulatory light chain of myosin. Does not bind calcium.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 47 interaction(s) predicted by orthology.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 47 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003774 motor activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008307 structural constituent of muscle
GO:0030898 actin-dependent ATPase activity
Biological Process
GO:0006200 ATP catabolic process
GO:0006936 muscle contraction
GO:0007519 skeletal muscle tissue development
GO:0008152 metabolic process
GO:0030049 muscle filament sliding
Cellular Component
GO:0016020 membrane
GO:0016459 myosin complex
GO:0016461 unconventional myosin complex
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID MGI:109318
InterPro IPR002048 EF-hand domain
PFAM PF00036
PF13202
PF13405
PRINTS
PIRSF
SMART SM00054
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q60605
PhosphoSite PhosphoSite-Q60605
TrEMBL Q642K0
UniProt Splice Variant
Entrez Gene 17904
UniGene Mm.208004
RefSeq NP_034990
MGI ID
MGI Symbol Myl6
OMIM
CCDS CCDS48728
HPRD
IMGT
EMBL AK167106 AK167191 AK168450 AK168869 BC026760 BC081470 BC089485 BC092214 CH466578 EF437355 U04443
GenPept AAC52278 AAH26760 AAH81470 AAH89485 AAH92214 ABS83521 BAE39255 BAE39321 BAE40353 BAE40688 EDL24571

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca