Version 5.4
Mus musculus Protein: Sap25
Summary
InnateDB Protein IDBP-620873.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sap25
Protein Name sin3 associated polypeptide
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000127076
InnateDB Gene IDBG-259063 (Sap25)
Protein Structure
UniProt Annotation
Function Involved in the transcriptional repression mediated by the mSIN3A but not the N-CoR corepressor complex. {ECO:0000269PubMed:16449650}.
Subcellular Localization Nucleus {ECO:0000269PubMed:16449650}. Cytoplasm {ECO:0000269PubMed:16449650}. Note=Shuttles between the nucleus and the cytoplasm.
Disease Associations
Tissue Specificity Widely expressed. {ECO:0000269PubMed:16449650}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:3802945
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q1EHW4
PhosphoSite PhosphoSite-
TrEMBL E9Q529
UniProt Splice Variant
Entrez Gene 751865
UniGene
RefSeq NP_001075431
MGI ID 2RMS
MGI Symbol Sap25
OMIM
CCDS CCDS39336
HPRD
IMGT
EMBL AC124730 AK158025 AK164339 AM275337
GenPept CAK36853

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca