Mus musculus Protein: Ddx39
Summary
InnateDB Protein IDBP-620907.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ddx39
Protein Name DEAD (Asp-Glu-Ala-Asp) box polypeptide 39
Synonyms 2610307C23Rik; BAT1; Ddx39a; DDXL; URH49;
Species Mus musculus
Ensembl Protein ENSMUSP00000132222
InnateDB Gene IDBG-172499 (Ddx39)
Protein Structure
UniProt Annotation
Function Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Can translocate to the cytoplasm in the presence of MX1. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0004386 helicase activity
GO:0005524 ATP binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006406 mRNA export from nucleus
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1915528
InterPro IPR001650 Helicase, C-terminal
IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR014014 RNA helicase, DEAD-box type, Q motif
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00271
PF00270
PRINTS
PIRSF
SMART SM00490
SM00487
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VDW0
PhosphoSite PhosphoSite-Q8VDW0
TrEMBL
UniProt Splice Variant
Entrez Gene 68278
UniGene Mm.28222
RefSeq
MGI ID
MGI Symbol Ddx39
OMIM
CCDS CCDS22460
HPRD
IMGT
EMBL AK088894 AK145927 AK146294 AK150997 AK162752 AK168079 BC020134
GenPept AAH20134 BAC40637 BAE26758 BAE27051 BAE30021 BAE37049 BAE40052