Version 5.4
Mus musculus Protein: Vsx2
Summary
InnateDB Protein IDBP-621176.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vsx2
Protein Name visual system homeobox 2
Synonyms Chx10; Hox-10; Hox10; or;
Species Mus musculus
Ensembl Protein ENSMUSP00000131009
InnateDB Gene IDBG-156854 (Vsx2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0008284 positive regulation of cell proliferation
GO:0008285 negative regulation of cell proliferation
GO:0043010 camera-type eye development
GO:0045165 cell fate commitment
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0060040 retinal bipolar neuron differentiation
GO:0060042 retina morphogenesis in camera-type eye
Cellular Component
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:88401
InterPro IPR001356 Homeobox domain
IPR003654 OAR domain
IPR009057 Homeodomain-like
PFAM PF00046
PF03826
PRINTS
PIRSF
SMART SM00389
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q6PDC1
UniProt Splice Variant
Entrez Gene 12677
UniGene Mm.4405
RefSeq XP_006515516
MGI ID
MGI Symbol Vsx2
OMIM
CCDS
HPRD
IMGT
EMBL AC110564 AK162139 BC058806 CH466590
GenPept AAH58806 BAE36748 EDL02809

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca