InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mier2

Summary

InnateDB Protein

IDBP-621197.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mier2

Protein Name

mesoderm induction early response 1, family member 2

Synonyms

2700087H15Rik; mKIAA1193;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000127387

InnateDB Gene

IDBG-170043 (Mier2)

Protein Structure

UniProt Annotation

Function

Transcriptional repressor. {ECO:0000250}.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00512, ECO:0000255PROSITE-ProRule:PRU00624}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003677	DNA binding
GO:0003682	chromatin binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0008150	biological_process

Cellular Component

GO:0005575	cellular_component
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

MGI:1917677

InterPro

IPR000949 ELM2 domain
IPR001005 SANT/Myb domain
IPR009057 Homeodomain-like

PFAM

PF01448
PF00249

PRINTS

PIRSF

SMART

SM00717

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q3U3N0

PhosphoSite

PhosphoSite-

TrEMBL

E9Q500

UniProt Splice Variant

Entrez Gene

70427

UniGene

Mm.334193

RefSeq

XP_006514144

MGI ID

MGI Symbol

Mier2

OMIM

CCDS

HPRD

IMGT

EMBL

AC100708 AK154672 AK173128 BC067013 BC080757 BC083321

GenPept

AAH67013 AAH80757 AAH83321 BAD32406 BAE32755