Version 5.4
Mus musculus Protein: Pax2
Summary
InnateDB Protein IDBP-621776.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pax2
Protein Name paired box gene 2
Synonyms Opdc; Pax-2;
Species Mus musculus
Ensembl Protein ENSMUSP00000134311
InnateDB Gene IDBG-170108 (Pax2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001655 urogenital system development
GO:0001656 metanephros development
GO:0001657 ureteric bud development
GO:0001658 branching involved in ureteric bud morphogenesis
GO:0001709 cell fate determination
GO:0001822 kidney development
GO:0001823 mesonephros development
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0042472 inner ear morphogenesis
GO:0043010 camera-type eye development
GO:0043067 regulation of programmed cell death
GO:0043069 negative regulation of programmed cell death
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0060231 mesenchymal to epithelial transition
GO:0072001 renal system development
GO:0090103 cochlea morphogenesis
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
Protein Structure and Domains
PDB ID MGI:97486
InterPro IPR001523 Paired domain
IPR009057 Homeodomain-like
PFAM PF00292
PRINTS PR00027
PIRSF
SMART SM00351
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL G3UZ20
UniProt Splice Variant
Entrez Gene 18504
UniGene Mm.192158
RefSeq
MGI ID
MGI Symbol Pax2
OMIM
CCDS
HPRD
IMGT
EMBL AC131105 AC138457
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca