Version 5.4
Mus musculus Protein: Cuedc2
Summary
InnateDB Protein IDBP-622004.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cuedc2
Protein Name CUE domain containing 2
Synonyms 3010002G01Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000129589
InnateDB Gene IDBG-172828 (Cuedc2)
Protein Structure
UniProt Annotation
Function Controls PGR and ESR1 protein levels through their targeting for ubiquitination and subsequent proteasomal degradation. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0031965 nuclear membrane
Protein Structure and Domains
PDB ID MGI:1914366
InterPro IPR003892 Ubiquitin system component Cue
IPR009060 UBA-like
PFAM PF02845
PRINTS
PIRSF
SMART SM00546
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CXX9
PhosphoSite PhosphoSite-Q9CXX9
TrEMBL
UniProt Splice Variant
Entrez Gene 67116
UniGene
RefSeq NP_077154
MGI ID
MGI Symbol Cuedc2
OMIM
CCDS CCDS29876
HPRD
IMGT
EMBL AB232359 AK013884 BC003442
GenPept AAH03442 BAB29035 BAE19943

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca