Version 5.4
Mus musculus Protein: Trmt61a
Summary
InnateDB Protein IDBP-623495.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trmt61a
Protein Name tRNA methyltransferase 61 homolog A (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000133128
InnateDB Gene IDBG-173460 (Trmt61a)
Protein Structure
UniProt Annotation
Function Catalytic subunit of tRNA (adenine-N(1)-)- methyltransferase, which catalyzes the formation of N(1)- methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0016429 tRNA (adenine-N1-)-methyltransferase activity
Biological Process
GO:0008150 biological_process
GO:0030488 tRNA methylation
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
GO:0031515 tRNA (m1A) methyltransferase complex
Protein Structure and Domains
PDB ID MGI:2443487
InterPro IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like
PFAM PF08704
PRINTS
PIRSF PIRSF017269
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q80XC2
PhosphoSite PhosphoSite-Q80XC2
TrEMBL
UniProt Splice Variant
Entrez Gene 328162
UniGene Mm.425747
RefSeq NP_001093262
MGI ID
MGI Symbol Trmt61a
OMIM
CCDS CCDS26184
HPRD
IMGT
EMBL AK032824 AK049138 BC051186
GenPept AAH51186 BAC28042 BAC33565

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca