Mus musculus Protein: Il5ra
Summary
InnateDB Protein IDBP-623953.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Il5ra
Protein Name interleukin 5 receptor, alpha
Synonyms CD125; CDw125; Il5r;
Species Mus musculus
Ensembl Protein ENSMUSP00000129781
InnateDB Gene IDBG-173890 (Il5ra)
Protein Structure
UniProt Annotation
Function This is the receptor for interleukin-5. The alpha chain binds to IL5.
Subcellular Localization Membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity Expressed on eosinophils and basophils. Also on B-cells.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004896 cytokine receptor activity
GO:0005515 protein binding
Biological Process
GO:0002437 inflammatory response to antigenic stimulus
GO:0019221 cytokine-mediated signaling pathway
GO:0032674 regulation of interleukin-5 production
GO:0071310 cellular response to organic substance
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:96558
InterPro IPR003961 Fibronectin, type III
IPR015321 Interleukin-6 receptor alpha, binding
PFAM PF00041
PF01108
PF09240
PRINTS
PIRSF
SMART SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P21183
PhosphoSite PhosphoSite-
TrEMBL Q05A81
UniProt Splice Variant
Entrez Gene 16192
UniGene Mm.3448
RefSeq NP_032396
MGI ID
MGI Symbol Il5ra
OMIM
CCDS CCDS20396
HPRD
IMGT
EMBL BC125374 CH466523 D90205
GenPept AAI25375 BAA14231 EDK99395