InnateDB Protein
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IDBP-624258.2
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Tex10
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Protein Name
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testis expressed gene 10
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000132498
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InnateDB Gene
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IDBG-146592 (Tex10)
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Protein Structure
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Function |
Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes. {ECO:0000269PubMed:22872859}.
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Subcellular Localization |
Nucleus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Nucleus, nucleolus {ECO:0000250}. Nucleus, nucleoplasm {ECO:0000269PubMed:22872859}. Cytoplasm {ECO:0000269PubMed:22872859}. Note=Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated |
Total |
2
[view]
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Protein-Protein |
2
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
10 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1344413
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InterPro |
IPR016024
Armadillo-type fold
IPR021133
HEAT, type 2
IPR024679
Pre-rRNA-processing protein IPI1/Testis-expressed sequence 10 protein
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PFAM |
PF12333
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q3URQ0
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PhosphoSite |
PhosphoSite-Q3URQ0
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
269536
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UniGene |
Mm.272025
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RefSeq |
NP_758508
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MGI ID |
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MGI Symbol |
Tex10
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OMIM |
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CCDS |
CCDS38760
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HPRD |
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IMGT |
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EMBL |
AK132870
AK141288
AL807247
BC151176
BC151177
CH466565
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GenPept |
AAI51177
AAI51178
BAE21398
BAE24638
CAM16567
EDL02335
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