InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tomm70a

Summary

InnateDB Protein

IDBP-624319.2

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tomm70a

Protein Name

translocase of outer mitochondrial membrane 70 homolog A (yeast)

Synonyms

2610044B22Rik; D16Ium22; D16Ium22e; D16Wsu109e; mKIAA0719; Tom70;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000129186

InnateDB Gene

IDBG-168434 (Tomm70a)

Protein Structure

UniProt Annotation

Function

Receptor that accelerates the import of all mitochondrial precursor proteins. {ECO:0000250}.

Subcellular Localization

Mitochondrion outer membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.

Disease Associations

Tissue Specificity

Expressed in the base region of the oxyntic and pyloric mucosae. {ECO:0000269PubMed:16476741}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	28 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

Cellular Component

GO:0005739	mitochondrion
GO:0005741	mitochondrial outer membrane
GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

MGI:106295

InterPro

IPR001440 Tetratricopeptide TPR1
IPR013026 Tetratricopeptide repeat-containing domain
IPR013105 Tetratricopeptide TPR2
IPR019734 Tetratricopeptide repeat

PFAM

PF00515
PF07719
PF13174
PF13176
PF13181

PRINTS

PIRSF

SMART

SM00028

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q9CZW5