Version 5.4
Mus musculus Protein: Smtn
Summary
InnateDB Protein IDBP-625005.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Smtn
Protein Name smoothelin
Synonyms smsmo;
Species Mus musculus
Ensembl Protein ENSMUSP00000133155
InnateDB Gene IDBG-140007 (Smtn)
Protein Structure
UniProt Annotation
Function Structural protein of the cytoskeleton. {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000250}. Note=Exhibits a filamentous organization. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
Protein Structure and Domains
PDB ID MGI:1354727
InterPro IPR001715 Calponin homology domain
IPR022189 Smoothelin cytoskeleton protein
IPR022613 Calmodulin-regulated spectrin-associated protein, CH domain
PFAM PF00307
PF12510
PF11971
PRINTS
PIRSF
SMART SM00033
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q921U8
PhosphoSite PhosphoSite-Q921U8
TrEMBL D3Z525
UniProt Splice Variant
Entrez Gene 29856
UniGene Mm.188516
RefSeq NP_001271358
MGI ID
MGI Symbol Smtn
OMIM
CCDS CCDS24366
HPRD
IMGT
EMBL AF064236 AF116517 AF116518 AF132449 AF195524 AF195525 AF218829 AF218830 AF218831 AF218832 AF218833 AF218834 AJ010305 AK030932 AK170516 AL713875 BC010599 BC066192 BC069836 BC069839
GenPept AAD29628 AAF01480 AAF25577 AAF25578 AAF25579 AAF25580 AAF67392 AAH10599 AAH66192 AAH69836 AAH69839 BAC27188 BAE41853 CAA09076

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca