Version 5.4
Mus musculus Protein: Ghitm
Summary
InnateDB Protein IDBP-625058.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ghitm
Protein Name growth hormone inducible transmembrane protein
Synonyms 1010001P14Rik; C77840; MICS1; PTD010; Tmbim5;
Species Mus musculus
Ensembl Protein ENSMUSP00000129712
InnateDB Gene IDBG-151182 (Ghitm)
Protein Structure
UniProt Annotation
Function Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c (By similarity). {ECO:0000250}.
Subcellular Localization Mitochondrion inner membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006915 apoptotic process
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1913342
InterPro IPR006214 Bax inhibitor 1-related
PFAM PF01027
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q91VC9
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 66092
UniGene Mm.486002
RefSeq NP_510963
MGI ID
MGI Symbol Ghitm
OMIM
CCDS CCDS26953
HPRD
IMGT
EMBL AF412297 AK093887 AK134592 AK146433 AK146853 AK151488 AK158904 AK159695 AK159724 AK164122 AK167970 AK168022 AK168678 AK168800 BC008622 BC010224
GenPept AAH08622 AAH10224 AAL07803 BAC04243 BAE22197 BAE27167 BAE27483 BAE30441 BAE34723 BAE35295 BAE35319 BAE37638 BAE39965 BAE40007 BAE40527 BAE40631

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca