Mus musculus Protein: Kirrel2
Summary
InnateDB Protein IDBP-625529.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kirrel2
Protein Name kin of IRRE like 2 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000131161
InnateDB Gene IDBG-169097 (Kirrel2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Highly expressed in beta-cells of the pancreatic islets. Expression is seen in podocytes of kidney glomeruli, and in the cerebellum and hindbrain at E12.5, in the spinal cord at E10.5, and in the retina and hypothalamus at E13.5. {ECO:0000269PubMed:12424224, ECO:0000269PubMed:12837264, ECO:0000269PubMed:19887377}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001933 negative regulation of protein phosphorylation
GO:0016337 single organismal cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0016021 integral component of membrane
GO:0036057 slit diaphragm
Protein Structure and Domains
PDB ID MGI:2442334
InterPro IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR013098 Immunoglobulin I-set
IPR013106 Immunoglobulin V-set domain
IPR013162 CD80-like, immunoglobulin C2-set
PFAM PF07679
PF07686
PF08205
PRINTS
PIRSF
SMART SM00408
SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7TSU7
PhosphoSite PhosphoSite-Q7TSU7
TrEMBL
UniProt Splice Variant
Entrez Gene 243911
UniGene Mm.452854
RefSeq
MGI ID
MGI Symbol Kirrel2
OMIM
CCDS
HPRD
IMGT
EMBL AY305303 BC052773
GenPept AAH52773 AAP72168